Two novel type 2 diabetes loci revealed through integration of TCF7L2 DNA occupancy and SNP association data.

BMJ Open Diabetes Res Care · 2014 · PMC4250976 · PMID 25469308

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showed a trendno p-value reported

The randomly generated gene list showed no significant over-representation of GWAS genes in the random gene set; in fact, it showed a trend of under-representation of GWAS genes in the random HOMER gene set, primarily due to the fact that some gene names in the NHGRI GWAS catalog are not RefSeq annotations (online supplementary table S13).

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highly significantno p-value reported

We previously mapped the genomic regions bound by TCF7L2 using ChIP (chromatin immunoprecipitation)-seq in the colorectal carcinoma cell line, HCT116, revealing an unexpected highly significant over-representation of genome-wide association studies (GWAS) loci associated primarily with endocrine (in particular T2D) and cardiovascular traits.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.