Mediation analysis demonstrates that trans-eQTLs are often explained by cis-mediation: a genome-wide analysis among 1,800 South Asians.

PLoS Genet · 2014 · PMC4256471 · PMID 25474530

Europe PMC DOI

hedged sentence

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closest p · 0.0× alpha

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boldest claim

The sentences

of marginal significanceP<10 −7actually significant

This is likely the case for many trans -eQTLs of marginal significance (5×10 −9 <P<10 −7 ), which are less likely to be cis -eQTLs than FDR-significant trans -eQTLs.

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