The discovery of potent, selective, and reversible inhibitors of the house dust mite peptidase allergen Der p 1: an innovative approach to the treatment of allergic asthma.

J Med Chem · 2014 · PMC4257840 · PMID 25365789

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a clear trendno p-value reported

There was a clear trend toward more lipophilic compounds showing better efficacy (compare compounds 27 , 29 , and 38 to compounds 45 , 47 , and 53 ).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.