Automated image-based assay for evaluation of HIV neutralization and cell-to-cell fusion inhibition.

This was the case for four inhibitory reagent-virus combinations (Figure 8 a, c, e and Additional file 1 : Table S1).Fourteen combinations that reached IC90 with a plasma dilution lower than 1:50 and 11 combinations that reached IC50 showed a trend towards decreased plaque area but could not be statistically confirmed (exemplified in Figure 8 b).

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