This effect was only marginally significant (p=0.09) likely due to considerable intertumoral heterogeneity in response to RCT as suggested by shallow dose–response curve (Figure 4 b).
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BAY 87-2243, a novel inhibitor of hypoxia-induced gene activation, improves local tumor control after fractionated irradiation in a schedule-dependent manner in head and neck human xenografts.
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