Dose-Dependent AMPK-Dependent and Independent Mechanisms of Berberine and Metformin Inhibition of mTORC1, ERK, DNA Synthesis and Proliferation in Pancreatic Cancer Cells.

PLoS One · 2014 · PMC4262417 · PMID 25493642

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The sentences

did not reach statistical significancep>0.07so close (0.05 < p ≤ 0.1)

At day 29, metformin was slightly more effective than berberine as assessed by tumor volume (p<0.05) but the effects did not reach statistical significance (p>0.07) when scored by tumor weight ( Fig. 2, B ).

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