As shown in Figure 2C , the glutamatergic component (i.e., the fEPSPs; Shaping, y = −0.9325x 2 +4.6626x+90.384; r 2 = 0.75; BSR, y = 0.343x 2 –4.8347x+96.88; r 2 = 0.55; P <0.001) presented a decreasing trend during the BSR stage.
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Involvement of the GABAergic septo-hippocampal pathway in brain stimulation reward.
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In addition, the decrease of fEPSP amplitudes was accompanied by an increasing trend of the main peak in the spectral power within the theta band (around 8–9 Hz) in time window C ( Figure 7 ).
Relationships between fPSP amplitudes and changes in hippocampal rhythmic activities during BSR sessions According to the present results, there is a negative trend in fEPSP amplitudes across BSR sessions, an occurrence not observed for fIPSP values ( Figure 2C, D ).