Epidermal growth factor receptor transactivation is required for mitogen-activated protein kinase activation by muscarinic acetylcholine receptors in HaCaT keratinocytes.

Int J Mol Sci · 2014 · PMC4264234 · PMID 25421240

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a clear trendno p-value reported

This was due to the high but variable basal activity of Akt observed in starved cells, which prevents the results from becoming statistically significant, although a clear trend towards activation by CCh and EGF was seen in all experiments shown here and later.

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