A decade of changes in clinical characteristics and management of elderly patients with non-ST elevation myocardial infarction admitted in Italian cardiac care units.

7 In the present analysis, the remarkable increase over time in the use of life-saving pharmacological therapies, coronary angiography and PCI as revascularisation modality was not paralleled by a significant trend towards the reduction of 30-day mortality, which, however, became evident, and statistically highly significant after adjustment for other powerful predictors of death such as diabetes, chronic kidney dysfunction, 18 19 and markers of ventricular dysfunction such as prior heart failure, low blood pressure, high baseline heart rate and Killip class.

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Clinical outcomes The crude rates of in-hospital major clinical events, including death, heart failure, stroke and major bleeding, did not show a significant trend during the decade of analysis ( table 3 ).

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