Integrin αV modulates the cellular pharmacology of copper and cisplatin by regulating expression of the influx transporter CTR1.

Oncoscience · 2014 · PMC4278295 · PMID 25594011

Europe PMC DOI

hedged sentence

0.0780

closest p · 1.6× alpha

0.0780

boldest claim

The sentences

did not reach statistical significancep = 0.078so close (0.05 < p ≤ 0.1)

5B , although the difference in IC 50 for the M21 and M21L did not reach statistical significance (IC 50 202.3 ± 23.5 versus 214.6 ± 16.7 μM, p = 0.078), an analysis of the slope of the overall curves in repeated experiments indicated a clear increase in sensitivity of the M21L cells to the higher Cu concentrations tested (p = 0.024).

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