Oxidative stress-related genetic polymorphisms are associated with the prognosis of metastatic gastric cancer patients treated with epirubicin, oxaliplatin and 5-fluorouracil combination chemotherapy.

PLoS One · 2014 · PMC4278770 · PMID 25545243

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borderline significantno p-value reported

In the Kaplan–Meier analysis of OS, the number of lesions and genotypes of rs662 in PON1 revealed a borderline significant association with OS ( Table 3 ).

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a clear trendno p-value reported

We found that TT carriers were likely to have a tendency of better PFS because the survival curve of TT carriers showed a clear trend of deviation from the curve of other patients, but the difference was not significant (for CC/CT and TT genotypes; median PFS: 171.0 and 267.0 days, respectively; p = 0.127).

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