Canagliflozin 100 and 300 mg showed numerical increases in HDL-C and decreases in triglycerides relative to placebo at week 26, but these differences did not reach statistical significance (Table 4 ).
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Efficacy and safety of canagliflozin in patients with type 2 diabetes mellitus inadequately controlled with metformin and sulphonylurea: a randomised trial.
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