Barely Significant
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HIV Tat protein affects circadian rhythmicity by interfering with the circadian system.

HIV Med · 2014 · PMC4285855 · PMID 24750691

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highly significantno p-value reported
A P value < 0.05 was considered statistically significant, and P < 0.01 highly significant.

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a negative trendno p-value reported
(b) The association between Tat protein concentration and the A / M of diastolic blood pressure (DBP) in patients with HIV/AIDS was not statistically significant ( R 2 = 0.0069; F = 0.63; P = 0.42), but showed a negative trend.

also in 2,741 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.