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Impact of the Pro12Ala polymorphism of the PPARγ2 gene on diabetes and obesity in a highly consanguineous population.

Indian J Endocrinol Metab · 2015 · PMC4287785 · PMID 25593831

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ests that the Ala 12 allele of the PPAR γ 2 gene may protect subjects with this polymorphism from type 2 diabetes.[ 3 4 ] This is not the case in our study that the frequency of Ala 12 allele was higher in the diabetic group and the difference between the group of diabetic and non-diabetic subjects did not reach statistical significance.

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