MED13-dependent signaling from the heart confers leanness by enhancing metabolism in adipose tissue and liver.

EMBO Mol Med · 2014 · PMC4287978 · PMID 25422356

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showed a trendno p-value reported

Interestingly, C16, C18, and C20 ceramides showed a trend to increase in hearts of fed MED13cTg versus fed WT mice, with few changes in the other ceramide species in fed or fasted mice (Supplementary Fig S2D).

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