Aβ reduction in BACE1 heterozygous null 5XFAD mice is associated with transgenic APP level.

Mol Neurodegener · 2015 · PMC4297413 · PMID 25567526

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failed to reach statistical significanceno p-value reported

A trend toward reduced levels of sAPPβ were observed at 6 and 9 months of age in female 5XFAD/BACE1 +/− compared to female 5XFAD/BACE1 +/+ , but these differences failed to reach statistical significance (Figure 5 C and D).

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