Regulation of Transforming Growth Factor β1, Platelet-Derived Growth Factor, and Basic Fibroblast Growth Factor by Silicone Gel Sheeting in Early-Stage Scarring.

Arch Plast Surg · 2015 · PMC4297801 · PMID 25606485

Europe PMC DOI

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approached significanceno p-value reported

Most patients in their study achieved clinical improvement with a reduction in firmness, pruritus, pain, and tenderness, but based on the cytokine mRNA levels, a comparison of a hypertrophic scar treated with silicone gel sheets with an untreated scar revealed that none of the changes approached significance.

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