Late-onset metastasis of renal cell carcinoma into a hot thyroid nodule: an uncommon finding not to be overlooked.

It also addressed various important points: (i) overall, the resected metastatic thyroid lesions were mostly solitary; (ii) patients surviving ≥ 3 years after the discovery of metastatic disease of the thyroid mostly (37%) had CCRC; (iii) thyroidectomy (performed in 41 out of 91 patients) resulted in improved median survival (30 months) in comparison with patients without surgery (20 months), but this did not reach statistical significance, possibly owing to the rather low number of subjects included [ 11 ].

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