a trend toward significanceP = 0.053
The multivariate analysis by stage indicated that a trend toward significance for opioid consumption as a risk factor in stage I patients ( P = 0.053).
The multivariate analysis by stage indicated that a trend toward significance for opioid consumption as a risk factor in stage I patients ( P = 0.053).
Our data suggest that the influence of opioids on cancer recurrence shows an important trend in the early (stage I) rather than later (stage II and III) stages.