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Joint feedback analysis modeling of nonesterified fatty acids in obese Zucker rats and normal Sprague-Dawley rats after different routes of administration of nicotinic acid.

J Pharm Sci · 2014 · PMC4303919 · PMID 24986056

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a clear trendno p-value reported
For all doses, there is a clear trend of markedly decreased variability in the extent of rebound as function of increased degrees of disease.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.