The total glutathione (GSH + GSSG) concentrations in the db / db mice were slightly lower than those in the age-matched db / m mice, although they did not reach statistical significance ( P = 0.12, 0.06, and 0.08, respectively).
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Noninvasive in vivo imaging of diabetes-induced renal oxidative stress and response to therapy using hyperpolarized 13C dehydroascorbate magnetic resonance.
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