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Protein phosphatase 2C-alpha knockdown reduces angiotensin II-mediated skeletal muscle wasting via restoration of mitochondrial recycling and function.

Skelet Muscle · 2014 · PMC4306116 · PMID 25625009

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Indeed, while it did not reach statistical significance, there appears to be a modest trend for increased LC3A gene expression with AngII, which may also explain the increase in LC3-II conversion over basal conditions with AngII.

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