In addition, after 2 weeks in the RCCS bioreactor, the spontaneously formed aggregates showed a trend (not significant) towards a greater mean area (2.98 ± 0.26 mm 2 ), compared to that of the preinduced aggregates (1.89 ± 1.28 mm 2 ) ( Figure 1 ).
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RCCS bioreactor-based modelled microgravity induces significant changes on in vitro 3D neuroglial cell cultures.
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