Comparison of hyaluronic acid-containing topical eye drops with carbomer-based topical ocular gel as a tear replacement in canine keratoconjunctivitis sicca: A prospective study in twenty five dogs.

Given the marked difference in the drop formulation of the HA-containing medication and the gel-based carbomer, a fully masked study was impossible, This clearly has an influence on both owner and veterinary observer’s assessment of ocular parameters, but given the highly significant improvement in conjunctival hyperemia and ocular comfort in this study, it is hoped that this study at least provides a preliminary basis for further better-masked evaluation of these novel tear replacement formulations.

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Ocular discharge was reduced from a score of 1.04 ± 0.82 to 0.70 ± 0.53, however, the decrease did not reach statistical significance.

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