STAT3 gene mutations and their association with pure red cell aplasia in large granular lymphocyte leukemia.

Comparing these 15 patients with the other seven LGL L-associated PRCA patients who were negative for STAT3 mutation, the clinical features did not differ (data not shown), although those with mutations showed a trend towards a younger age than those without mutations (median age, 52.5 years and 77.5 years, respectively; P = 0.071).

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