Corresponding herewith, Fcgr2b −/− x Cd55 −/− mice showed a trend toward enhanced cartilage destruction and immune cell infiltration (Figure 5 C) with more Gr1 + CD11b + granulocytes present locally in the synovial tissue (Figure 5 D).
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CD55 deposited on synovial collagen fibers protects from immune complex-mediated arthritis.
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