Colonic permeability and electrophysiology (Ussing chambers) Colonic permeability to FD4 in basal condition displayed a highly significant interaction between maternal ATB treatment and offspring late diet (P < 0.01) ( Table 2 ).
However, under oxidative condition, the treatment by age interaction tended towards significance (P = 0.066), showing that HRP permeability tended to be transiently higher in offspring born to ATB-treated mothers at day 14 compared to day 42 (P < 0.10), while these differences were not significant in CTL offspring and were not different from values in ATB offspring aged 42 days ( Table 1 ).