Cells from both lines were able to polarise under normal conditions; however, treatment with 20 m M LiCl and 5 μ M BIO reduced polarity as demonstrated by a reduction in displacement, but this did not reach statistical significance (displacement SF188 control 176.5±74.6, LiCl 20 m M 52.5±15.3, BIO 5 μ mol 107.2±61.7, KNS42 control 28.6±8.23, LiCl 20 m M 14.7±2.35, BIO 5 μ mol 14.19±1.9).
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Cell migration in paediatric glioma; characterisation and potential therapeutic targeting.
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