Upregulation of IGF-1R expression during neoadjuvant therapy predicts poor outcome in breast cancer patients.

PLoS One · 2015 · PMC4334229 · PMID 25680198

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However, IGF-1R showed a trend towards more downregulation in the endocrine-treated group; IGF-1R was downregulated in 4/13 tumors and upregulated in 1/13 tumors.

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