A genome scan identified a single, broad, highly significant peak on Chr 2 in each population, and those peaks overlap with each other and with the initial candidate interval for TRD ( Fig. 3 C-E ).
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A multi-megabase copy number gain causes maternal transmission ratio distortion on mouse chromosome 2.
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The sentences
Note that some p -values in comparisons involving (NZO/HILtJxWSB/EiJ)F1 crosses failed to reach statistical significance due to the small sample size, but the trends were always consistent with those in DO dams with TRD.