nominally significantP <0.05
WHRadjBMI SNPs also showed enrichment for directional consistency among nominally significant ( P <0.05) associations with these traits and also with fasting and 2-hour glucose, diastolic and systolic blood pressure (DBP, SBP), BMI and coronary artery disease (CAD) ( P binomial <0.05/23=0.0022, Extended Data Table 2 ); these results were generally supported by meta-regression analysis of the regression coefficient-estimates ( Supplementary Table 10 ).