The association between the neutrophil-to-lymphocyte ratio and mortality in critical illness: an observational cohort study.

After multivariable adjustments, there was a significant trend for increasing mortality with increasing quartile of NLR; however, this did not follow a stepwise pattern as it did in the primary analysis (adjusted ORs: first quartile = reference value; second quartile = 1.55 (95% CI, 1.08 to 2.23), P = 0.02); third quartile = 1.30 (95% CI, 0.90 to 1.86), P = 0.2); fourth quartile = 1.99 (95% CI, 1.41 to 2.82), P < 0.001).

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