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Plasma concentrations of BDNF and IGF-1 in abstinent cocaine users with high prevalence of substance use disorders: relationship to psychiatric comorbidity.

PLoS One · 2015 · PMC4348520 · PMID 25734326

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The association of plasma IGF-1 concentrations with age was not affected by the pathological use of cocaine, although the association of IGF-1 and IGFBP-3 did not reach statistical significance after correcting it in abstinent cocaine users.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.