Mechanism of Action of 2-Aminobenzamide HDAC Inhibitors in Reversing Gene Silencing in Friedreich's Ataxia.

Front Neurol · 2015 · PMC4350406 · PMID 25798128

Europe PMC DOI

hedged sentence

0.0900

closest p · 1.8× alpha

0.0900

boldest claim

The sentences

did not reach statistical significancep value = 0.09so close (0.05 < p ≤ 0.1)

We find that siHDAC1 and siHDAC3 were potent inducers of FXN gene expression (Figure 3 C), although FXN up-regulation with siHDAC3 treatment did not reach statistical significance ( p value = 0.09).

also in 111,027 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.