Dexmedetomidine inhibits Tetrodotoxin-resistant Nav1.8 sodium channel activity through Gi/o-dependent pathway in rat dorsal root ganglion neurons.

Mol Brain · 2015 · PMC4350947 · PMID 25761941

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did not reach statistical significanceno p-value reported

Although the increase did not reach statistical significance, it totally removed the inhibitory effect of DEX on Na v 1.8 currents (Figure 5 G and I).

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