Blockade of PD-1/PD-L1 promotes adoptive T-cell immunotherapy in a tolerogenic environment.

Whilst there was a trend toward an increase in the total number of OT-I producing IFN-γ after administration of αPD-1 or αPD-L1, this failed to reach statistical significance, most likely due to the low number of mice sampled ( Fig. 1E ).

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