Nuclear expression of p65 (RelA) in patients receiving post-operative radiotherapy for locally advanced squamous cell carcinoma of the head and neck.

BMC Cancer · 2015 · PMC4352566 · PMID 25868613

Europe PMC DOI

hedged sentences

0.0500

closest p · 1.0× alpha

0.0800

boldest claim

The sentences

borderline significantp ≤ 0.05actually significant

Those variables showing a significant or borderline significant (p ≤ 0.05) association with treatment outcomes on univariate analyses were also included in a multivariate analysis performed with the Cox proportional hazards model.

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borderline significancep = 0.052so close (0.05 < p ≤ 0.1)

On multivariate analysis, KPS ≥80 (risk ratio [RR] 2.23; p = 0.012), HPV-positivity (RR 5.83; p = 0.020), T1-T2 (RR 1.38; p = 0.048), N0-N2a (RR 2.72; p = 0.005) and complete resection (RR 2.02; p = 0.049) were positively associated with OS; p65-negativity achieved borderline significance (RR 3.02; p = 0.052).

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showed a trendp = 0.08so close (0.05 < p ≤ 0.1)

Hemoglobin levels showed a trend (RR 1.76; 95%-CI 0.94-3.26; p = 0.08), and extent of resection was not significant (RR 1.81; 95%-CI 0.88-3.52; p = 0.11).

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