borderline non-significantP = 0.058
At Week 48, a baseline ADCS-IADL score indicating a more severe disease status led to an increased estimate of the probability of no decline ( P = 0.020), while an MMSE score ≤12 at baseline reduced the estimate ( P = 0.040); treatment with the 13.3 mg/24 h versus the 9.5 mg/24 h patch was borderline non-significant ( P = 0.058).