A kinetic study of the main guaco metabolites using syrup formulation and the identification of an alternative route of coumarin metabolism in humans.

PLoS One · 2015 · PMC4355590 · PMID 25757073

Europe PMC DOI

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quite significantno p-value reported

The dietary exposure to coumarin is therefore quite significant in humans, and determining the metabolic fate of COU is important to access the possible dependence of coumarin-induced toxicity on metabolism.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.