Plasma levels of matrix metalloproteinase-2, -3, -10, and tissue inhibitor of metalloproteinase-1 are associated with vascular complications in patients with type 1 diabetes: the EURODIAB Prospective Complications Study.

Cardiovasc Diabetol · 2015 · PMC4355971 · PMID 25848912

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a significant trendno p-value reported

In addition, a significant trend across the severity of retinopathy was observed for increasing plasma levels of MMP-2 (p-trend = 0.017).

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.