Cattle encephalon glycoside and ignotin injection improves cognitive impairment in APPswe/PS1dE9 mice used as multitarget anti-Alzheimer's drug candidates.

Neuropsychiatr Dis Treat · 2015 · PMC4356454 · PMID 25784809

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did not reach statistical significanceno p-value reported

Administration of CEGI for 1 month tended to increase body weight, but the increase did not reach statistical significance (before injection, nTg 32.0±1.06 g, Tg 32.2±1.64 g, Tg + CEGI-L 32.6±1.88 g, Tg + CEGI-H 32.5±2.04 g, Tg + donepezil 32.4±2.21 g; after injection nTg 32.6± 1.19 g, Tg 33.1±1.39 g, Tg + CEGI-L 33.5±1.46 g, Tg + CEGI-H 33.8±1.69 g, Tg + donepezil 33.3±1.97 g).

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