Aurora kinase A has a significant role as a therapeutic target and clinical biomarker in endometrial cancer.

Int J Oncol · 2015 · PMC4356503 · PMID 25625960

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showed a trendno p-value reported

Immunohistochemical analysis of apoptosis (TUNEL analysis) and proliferation (Ki67) after treatment (on day 28) showed that the combination of AURKA siRNA and paclitaxel significantly increased the number of TUNEL-positive cells (P<0.05) and showed a trend for decreasing the number of Ki67-positive cells ( Fig. 6A–C ).

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