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Oral antigen exposure in newborn piglets circumvents induction of oral tolerance in response to intraperitoneal vaccination in later life.

BMC Vet Res · 2015 · PMC4357157 · PMID 25889479

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a strong trendno p-value reported
route one month later showed significantly lower anti-OVA immunoglobulin (Ig) A titres and a strong trend towards lower anti-OVA IgM, IgG1, IgG2 and IgG titres relative to the i.p. control group indicating induction of oral tolerance [ 27 ].

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