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A systems biology approach reveals the dose- and time-dependent effect of primary human airway epithelium tissue culture after exposure to cigarette smoke in vitro.

Bioinform Biol Insights · 2015 · PMC4357630 · PMID 25788831

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a clear trendno p-value reported
A qualitatively similar response was observed at 2 and 4 hours post-exposure for both doses with a clear trend toward a stronger response with the high dose.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.