Second-generation antipsychotics and neuroleptic malignant syndrome: systematic review and case report analysis.

Drugs R D · 2015 · PMC4359181 · PMID 25578944

Europe PMC DOI

hedged sentences

0.0800

closest p · 1.6× alpha

0.1000

boldest claim

The sentences

a statistical trendp = 0.08so close (0.05 < p ≤ 0.1)

There was a statistical trend for an association between antidepressant use in the past week and a higher global severity (37.0 ± 9.6 vs. 32.4 ± 8.7; p = 0.08) but this disappeared after adjusting for the type of antipsychotic.

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did not reach statistical significancep = 0.10so close (0.05 < p ≤ 0.1)

While a degree of hyperpyrexia was almost ubiquitary, higher temperatures were less commonly observed for aripiprazole (58.3 %) than other SGAs, but this difference did not reach statistical significance ( p = 0.10).

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