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TWIST1 and TWIST2 promoter methylation and protein expression in tumor stroma influence the epithelial-mesenchymal transition-like tumor budding phenotype in colorectal cancer.

Oncotarget · 2015 · PMC4359262 · PMID 25528769

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An inverse relationship between higher budding counts and TWIST2 methylation was also noted ( p = 0.0724) but did not reach statistical significance.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.