Apolipoprotein L1, income and early kidney damage.

Compared with persons with low-risk APOL1 , high-risk persons were at 50% higher odds of eGFR < 75, but estimates did not reach statistical significance (Table 2 ).

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Thus, despite the highly significant association between high-risk APOL1 and kidney disease among African Americans in multiple recent studies [ 3 , 4 , 7 , 10 ], it may not be the only contributor to early kidney disease in this population.

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