Effect of a topical copper indomethacin gel on inflammatory parameters in a rat model of osteoarthritis.

Drug Des Devel Ther · 2015 · PMC4362896 · PMID 25792809

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did not reach statistical significanceno p-value reported

In addition, the lowest dose (0.25 g/kg) of gel showed the greatest decrease in serum IL-6 level in comparison to all other treatment groups, including the higher doses of Cu-Indo, but this did not reach statistical significance by Tukey post hoc multicomparisons test ( Tables 2 and 3 ).

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