MicroRNA-125b modulates inflammatory chemokine CCL4 expression in immune cells and its reduction causes CCL4 increase with age.

Aging Cell · 2015 · PMC4364832 · PMID 25620312

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did not reach statistical significanceP < 0.05actually significant

In contrast, naïve CD8 T cells from old adults showed an increase of CCL4 mRNA after activation but did not reach statistical significance, as well as a reduction of miR-125b after activation which was only significant at 48 h ( P < 0.05).

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