approached significancep ≤ 0.1
Lastly, complete-data analysis (Additional files 6 , 7 : Tables S6-S7) showed similar overall trends as the multiple imputation analysis with rs3817198 remaining significantly associated (p ≤ 0.05) with absolute measures of breast density in Caucasian women, although SNPs rs3803662 and rs4973768 only approached significance (p ≤ 0.1) with absolute volume density and volume percent density, respectively, in African-American women, likely due to the decreased sample size in the complete-data analysis leading to a loss of statistical power.